CAS No. 7380-40-7 | Bergamotine
Name: Bergamotine CAS No. 7380-40-7 MF:C21H22O4 MW:338.4 Purity:98% Package: 10mg,25mg,50mg,100mg,250mg Worldwide Delivery
Categories:
Biochemicals
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Product introduction
Introduction and application of CAS No. 7380-40-7 | Bergamotine
Synonyms:BERGAMOTINE;
5-GERANYLOXYPSORALEN;
4-GERANYLOXYPSORALEN;
AKOS 214-13;GF-I-2;
BERGAMOTIN WITH HPLC;
Bergamotine, Bergaptin;
4-[[(E)-3,7-Dimethyl-2,6-octadienyl]oxy]-7H-furo[3,2-g][1]benzopyran-7-one
Specification:
|
ITEMS |
SPECIFICATION |
|
CAS |
7380-40-7 |
|
MF |
C21H22O4 |
|
MW |
338.4 |
|
Melting point |
75-80 °C |
|
Boiling point |
503.7±50.0 °C |
|
Density |
1.153±0.06 g/cm3 |
|
Color |
white to light yellow |
|
Solubility |
Soluble in DMSO (a little), methanol (a little) |
|
Form |
Solid |
|
Storage condition |
2-8°C |
Overview:
Bergamottin, also known as bergamot, bergamot, and bergamot, is found in citrus fruits such as bergamot, pomelo, and grapefruit, as well as some traditional Chinese medicinal materials such as Qianghuo. It is insoluble in water and soluble in methanol. , ethanol, ethyl acetate and other organic solvents. Bergamot is a natural furanocoumarin compound. However, high-purity bergamot is expensive and scarce on the market. Therefore, most activity studies are limited to in vitro cell experiments, and there are relatively few further in vivo metabolism studies. . There are also few reports on the "quick and effective extraction, isolation and purification of bergamot from natural plants". Pomelo is a fruit abundant in southern my country. However, the pomelo peel, which accounts for 43% to 48% of the whole fruit, is usually discarded when eaten fresh or during food processing. This not only causes serious waste of resources, but also causes environmental pollution. Research on extracting high-purity bergamot from pomelo peel can further strengthen the development and utilization of pomelo peel resources, reduce production costs, improve raw material utilization, and provide a working basis for research on the pharmaceutical activity of bergamot and its related mechanism of action. and technical support to maximize the added value of Pomelo. Applied pharmaceutical activity studies have shown that bergamot can inactivate a variety of drug metabolism-related enzymes in the cytochrome P450 enzyme system, thereby affecting the absorption of drugs in the gastrointestinal tract and increasing the bioavailability of oral drugs. In addition, bergamot can also inhibit the proliferation, invasion and migration of cancer cells, and has various biological activities such as anti-cancer, antibacterial, and anti-mutagenicity, and has attracted widespread attention.
Chemical properties:
White needle-shaped crystals, soluble in organic solvents such as methanol, ethanol, DMSO, etc., derived from lemon pulp with the highest content of Adenophora ginseng and Qianghuo.
Usage:
Bergamot has antitussive, asthmatic, and expectorant effects, and can be used for content determination/identification/pharmacological experiments, etc.
Package and transportation :
Package: 10mg,25mg,50mg,100mg,250mg
Transportation: by courier/ by air/ by sea
Key words:
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